2024
Therapeutic effect of prophylactic administration of synthetic tryptophan metabolites on silicone breast implant-induced Capsular contracture formation.
Yidan Xu*, Han Yang*, Shujie Xu*, Yuchen Zhang, Jianhua Gao#, Yao Yao# (* equal contribution, # corresponding author)
Plastic and Reconstructive Surgery Under Review 2024 Article
Under Review
Therapeutic effect of prophylactic administration of synthetic tryptophan metabolites on silicone breast implant-induced Capsular contracture formation.
Yidan Xu*, Han Yang*, Shujie Xu*, Yuchen Zhang, Jianhua Gao#, Yao Yao# (* equal contribution, # corresponding author)
Plastic and Reconstructive Surgery Under Review 2024 Article
Under Review
Lipophagy Enhances Fat Graft Retention by Stimulating Dedifferentiation of Mature Adipocytes and Modulating Inflammation.
Shujie Xu*, Xinhui Wang*, Yidan Xu*, Han Yang, Yunjun Liao, Qiang Chang, Junrong Cai, Feng Lu, Jianhua Gao (* equal contribution)
Plastic and Reconstructive Surgery Accepted 2024 Article
Waiting for publication
Lipophagy Enhances Fat Graft Retention by Stimulating Dedifferentiation of Mature Adipocytes and Modulating Inflammation.
Shujie Xu*, Xinhui Wang*, Yidan Xu*, Han Yang, Yunjun Liao, Qiang Chang, Junrong Cai, Feng Lu, Jianhua Gao (* equal contribution)
Plastic and Reconstructive Surgery Accepted 2024 Article
Waiting for publication
Mesenchymal stem cells-derived extracellular vesicles for wound healing and skin regeneration: A systematic review and meta-analysis of preclinical studies.
Yufan Zhu, Han Yang, Meiqi Liu, Zhixin Xue, Haojing Tang, Xihang Chen, Yunjun Liao
Journal of Translational Medicine Accepted 2024 Meta-Analysis
Waiting for publication
Mesenchymal stem cells-derived extracellular vesicles for wound healing and skin regeneration: A systematic review and meta-analysis of preclinical studies.
Yufan Zhu, Han Yang, Meiqi Liu, Zhixin Xue, Haojing Tang, Xihang Chen, Yunjun Liao
Journal of Translational Medicine Accepted 2024 Meta-Analysis
Waiting for publication
Correction of infraorbital dark circles using autologous adipose-derived collagen.
Sousan Cheong*, Han Yang*, Choukuan Hao, Feng Lu#, Yunfan He# (* equal contribution, # corresponding author)
Aesthetic Plastic Surgery 2024 Article
This study evaluates a novel treatment for infraorbital dark circles using adipose-derived extracellular matrix concentrate (ACF) injections. Ninety-four female patients aged 20-38 received ACF fillers, with follow-ups conducted over eight months. Results showed a high satisfaction rate, with 86% of participants reporting significant improvements in skin brightness, tightness, and smoothness. Over 97% were rated as “improved” by independent assessors, with no adverse effects noted. The findings suggest that ACF fillers provide effective periorbital rejuvenation and bio-stimulation with regenerative properties.
Correction of infraorbital dark circles using autologous adipose-derived collagen.
Sousan Cheong*, Han Yang*, Choukuan Hao, Feng Lu#, Yunfan He# (* equal contribution, # corresponding author)
Aesthetic Plastic Surgery 2024 Article
This study evaluates a novel treatment for infraorbital dark circles using adipose-derived extracellular matrix concentrate (ACF) injections. Ninety-four female patients aged 20-38 received ACF fillers, with follow-ups conducted over eight months. Results showed a high satisfaction rate, with 86% of participants reporting significant improvements in skin brightness, tightness, and smoothness. Over 97% were rated as “improved” by independent assessors, with no adverse effects noted. The findings suggest that ACF fillers provide effective periorbital rejuvenation and bio-stimulation with regenerative properties.
2023
Mesenchymal stem cell-based therapy for autoimmune-related fibrotic skin diseases: systemic sclerosis and sclerodermatous graft-versus-host disease
Han Yang*, Sousan Cheong*, Yunfan He, Feng Lu (* equal contribution)
Stem Cell Research & Therapy 2023 Review
Systemic sclerosis (SSc) and sclerodermatous GVHD are autoimmune diseases characterized by severe skin fibrosis due to immune dysfunction. Mesenchymal stem cell (MSC)-based therapies show promise in regulating the immune system, reducing oxidative stress, and inhibiting fibrosis. This review focuses on the role of MSC therapies in treating SSc and Scl-GVHD through these mechanisms.
Mesenchymal stem cell-based therapy for autoimmune-related fibrotic skin diseases: systemic sclerosis and sclerodermatous graft-versus-host disease
Han Yang*, Sousan Cheong*, Yunfan He, Feng Lu (* equal contribution)
Stem Cell Research & Therapy 2023 Review
Systemic sclerosis (SSc) and sclerodermatous GVHD are autoimmune diseases characterized by severe skin fibrosis due to immune dysfunction. Mesenchymal stem cell (MSC)-based therapies show promise in regulating the immune system, reducing oxidative stress, and inhibiting fibrosis. This review focuses on the role of MSC therapies in treating SSc and Scl-GVHD through these mechanisms.
2022
Clinical application and mechanism exploration of autologous fat grafting in hypertrophic scar treatment
Han Yang, Yunfan He, Feng Lu
National Medicine Journal of China 2022 Review
Autologous fat transfer has been used not only for filling soft tissue defects, but has also shown great potential for inhibiting fibrosis and promoting scar tissue remodeling in recent years. In this paper, we focus on the treatment of hypertrophic scars (HTSs) and review the possible mechanisms and clinical applications of adipose tissue and its derivatives for the treatment of HTSs, aiming to further develop the application of adipose transplantation and adipose stem cells, and provide more new strategies for the comprehensive treatment of HTSs.
Clinical application and mechanism exploration of autologous fat grafting in hypertrophic scar treatment
Han Yang, Yunfan He, Feng Lu
National Medicine Journal of China 2022 Review
Autologous fat transfer has been used not only for filling soft tissue defects, but has also shown great potential for inhibiting fibrosis and promoting scar tissue remodeling in recent years. In this paper, we focus on the treatment of hypertrophic scars (HTSs) and review the possible mechanisms and clinical applications of adipose tissue and its derivatives for the treatment of HTSs, aiming to further develop the application of adipose transplantation and adipose stem cells, and provide more new strategies for the comprehensive treatment of HTSs.
2021
Anatomic Measurement and Variability Analysis of the Anterior Talofibular Ligament and Calcaneofibular Ligament of the Ankle
Han Yang*, Minghao Su*, Zhimin Chen*, Rongmei Qu, Zhirong Yuan, Jiajie Yuan, Shanli He, Zeyu Li, Chang Liu, Zhaoming Xiao, Haibin Liang, Jun Ouyang, Jingxing Dai (* equal contribution)
Orthopaedic Journal of Sports Medicine 2021 Article
This study analyzed the anatomy of the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL) in 66 ankle specimens. It found significant variability in the size and shape of the ATFL, while the angle between the ATFL and CFL remained consistent. Most CFLs attached anterior to the tip of the fibula, rather than directly at the tip. These findings provide essential anatomical data to improve surgical treatment of lateral ankle ligament injuries.
Anatomic Measurement and Variability Analysis of the Anterior Talofibular Ligament and Calcaneofibular Ligament of the Ankle
Han Yang*, Minghao Su*, Zhimin Chen*, Rongmei Qu, Zhirong Yuan, Jiajie Yuan, Shanli He, Zeyu Li, Chang Liu, Zhaoming Xiao, Haibin Liang, Jun Ouyang, Jingxing Dai (* equal contribution)
Orthopaedic Journal of Sports Medicine 2021 Article
This study analyzed the anatomy of the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL) in 66 ankle specimens. It found significant variability in the size and shape of the ATFL, while the angle between the ATFL and CFL remained consistent. Most CFLs attached anterior to the tip of the fibula, rather than directly at the tip. These findings provide essential anatomical data to improve surgical treatment of lateral ankle ligament injuries.